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GDF8 Promotes the Cell Invasiveness in Human Trophoblasts by Upregulating the Expression of Follistatin-Like 3 Through the ALK5-SMAD2/3 Signaling Pathway

Growth differentiation factor 8 (GDF8) and its antagonist follistatin-like 3 (FSTL3) are expressed in the placenta during early pregnancy. These two factors may have a role to play in the regulation of normal placentation. However, whether GDF8 can regulate the expression of FSTL3 in human trophobla...

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Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Xie, Jiamin, Zhu, Hua, Chang, Hsun-Ming, Klausen, Christian, Dong, Minyue, Leung, Peter C. K.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655915/
https://ncbi.nlm.nih.gov/pubmed/33195207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.573781
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