Safety and tolerability of topotecan-eluting radiopaque microspheres for hepatic chemoembolization in a rabbit preclinical model

PURPOSE: Topotecan is a camptothecin analogue with potential advantages over irinotecan for transarterial chemoembolization (TACE) of hepatic colorectal metastases including greater anti-neoplastic activity without enzymatic activation. The purpose of this study was to assess safety and tolerability...

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Detalhes bibliográficos
Publicado no:Cardiovasc Intervent Radiol
Main Authors: Mikhail, Andrew S., Levy, Elliot B., Krishnasamy, Venkatesh P., Woods, David L., Esparza-Trujillo, Juan A., Bakhutashvili, Ivane, Banovac, Filip, Wakim, Paul G., Negussie, Ayele H., Tang, Yiqing, Henman, Alexander, Willis, Sean L., Karanian, John W., Pritchard, William F., Lewis, Andrew L., Wood, Bradford J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655617/
https://ncbi.nlm.nih.gov/pubmed/32803282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00270-020-02609-z
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