Safety and tolerability of topotecan-eluting radiopaque microspheres for hepatic chemoembolization in a rabbit preclinical model

PURPOSE: Topotecan is a camptothecin analogue with potential advantages over irinotecan for transarterial chemoembolization (TACE) of hepatic colorectal metastases including greater anti-neoplastic activity without enzymatic activation. The purpose of this study was to assess safety and tolerability...

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Published in:Cardiovasc Intervent Radiol
Main Authors: Mikhail, Andrew S., Levy, Elliot B., Krishnasamy, Venkatesh P., Woods, David L., Esparza-Trujillo, Juan A., Bakhutashvili, Ivane, Banovac, Filip, Wakim, Paul G., Negussie, Ayele H., Tang, Yiqing, Henman, Alexander, Willis, Sean L., Karanian, John W., Pritchard, William F., Lewis, Andrew L., Wood, Bradford J.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655617/
https://ncbi.nlm.nih.gov/pubmed/32803282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00270-020-02609-z
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