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A 5-HT(1D)-Receptor Agonist Protects Dravet Syndrome Mice from Seizure and Early Death
Mutations in the SCN1A gene encoding the Nav1.1 sodium channel cause several forms of epilepsy, the most severe is Dravet syndrome (DS). DS patients are at high risk for sudden death and seizures are often triggered by fever or hyperthermia. To improve understanding of how serotonergic ligands might...
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| Publicado no: | Eur J Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7655614/ https://ncbi.nlm.nih.gov/pubmed/32394465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14776 |
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