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Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells
The age-dependent decline in stem cell function plays a critical role in aging, although the molecular mechanisms remain unclear. PTRF/Cavin-1 is an essential component in the biogenesis and function of caveolae, which regulates cell proliferation, endocytosis, signal transduction and senescence. Th...
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| Pubblicato in: | Aging (Albany NY) |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7655181/ https://ncbi.nlm.nih.gov/pubmed/33087586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103729 |
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