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Gracilin A derivatives target early events in Alzheimer’s disease: in vitro effects on neuroinflammation and oxidative stress
The search for compounds capable of targeting early pathological changes of Alzheimer`s disease (AD), such as oxidative stress and neuroinflammation, is an important challenge. Gracilin A derivatives were recently synthesized, using a pharmacophore-directed retrosynthesis strategy, and found to poss...
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| Publicado en: | ACS Chem Neurosci |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7654966/ https://ncbi.nlm.nih.gov/pubmed/31387354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00329 |
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