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Is OR "portable" in meta-analysis? Time to consider bivariate generalized linear mixed model.

Objectives: A recent paper by Doi et al. advocated completely replacing the relative risk (RR) with the odds ratio (OR) as the effect measure used to report the association between a treatment and a binary outcome in clinical trials and meta-analyses. Besides some practical advantages of RR over OR...

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Bibliographic Details
Published in:medRxiv
Main Authors: Xiao, Mengli, Chen, Yong, Cole, Stephen R, MacLehose, Richard, Richardson, David, Chu, Haitao
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654874/
https://ncbi.nlm.nih.gov/pubmed/33173884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.05.20226811
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