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Cannabinoid receptor type 1 antagonist inhibits progression of obesity‐associated nonalcoholic steatohepatitis in a mouse model by remodulating immune system disturbances

SCOPE: This study investigated whether AM251, a cannabinoid receptor type 1 (CB1) antagonist, ameliorates hepatic levels of metabolic abnormalities and inflammatory responses in a murine nonalcoholic steatohepatitis (NASH) model via reversal of disturbances in the immune system. METHODS AND RESULTS:...

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Dettagli Bibliografici
Pubblicato in:Immun Inflamm Dis
Autori principali: Chen, Chin‐Chang, Chang, Zi‐Yu, Tsai, Fuu‐Jen, Chen, Shih‐Yin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654409/
https://ncbi.nlm.nih.gov/pubmed/32798334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.338
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