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The Pharmacokinetics of DEX in Infants and Children following Orthotopic Liver Transplantation

BACKGROUND: Dexmedetomidine (DEX) is a sedative and analgesic that is frequently used post-operatively in children following liver transplantation. Hepatic dysfunction, and including alterations in drug clearance, are common immediately following liver transplantation. However, the pharmacokinetics...

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Publicat a:Anesth Analg
Autors principals: Damian, Mihaela A, Hammer, Gregory B, Elkomy, Mohammed H, Frymoyer, Adam, Drover, David R, Su, Felice
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654335/
https://ncbi.nlm.nih.gov/pubmed/30198929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000003761
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