Elucidating the Basis for Permissivity of the MT-4 T-Cell Line to Replication of an HIV-1 Mutant Lacking the gp41 Cytoplasmic Tail

HIV-1 encodes an envelope glycoprotein (Env) that contains a long cytoplasmic tail (CT) harboring trafficking motifs implicated in Env incorporation into virus particles and viral transmission. In most physiologically relevant cell types, the gp41 CT is required for HIV-1 replication, but in the MT-...

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Udgivet i:J Virol
Main Authors: Fernandez, Melissa V., Hoffman, Huxley K., Pezeshkian, Nairi, Tedbury, Philip R., van Engelenburg, Schuyler B., Freed, Eric O.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654282/
https://ncbi.nlm.nih.gov/pubmed/32938764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01334-20
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