Biophysical and Dynamic Characterization of Fine-Tuned Binding of the Human Respiratory Syncytial Virus M2-1 Core Domain to Long RNAs

The human respiratory syncytial virus (hRSV) M2-1 protein functions as a processivity and antitermination factor of the viral polymerase complex. Here, the first evidence that the hRSV M2-1 core domain (cdM2-1) alone has an unfolding activity for long RNAs is presented and the biophysical and dynami...

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Publicado en:J Virol
Autores principales: Caruso, Icaro P., Guimarães, Giovana C., Machado, Vitor B., Fossey, Marcelo A., Willbold, Dieter, Almeida, Fabio C. L., Souza, Fátima P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Structure and Assembly
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654269/
https://ncbi.nlm.nih.gov/pubmed/32938771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01505-20
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