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Novel loss-of-function variants in TRIO are associated with neurodevelopmental disorder: case report

BACKGROUND: Damaging variants in TRIO have been associated with moderate to severe neurodevelopmental disorders in humans. While recent work has delineated the positional effect of missense variation on the resulting phenotype, the clinical spectrum associated with loss-of-function variation has yet...

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Dades bibliogràfiques
Publicat a:BMC Med Genet
Autors principals: Schultz-Rogers, Laura, Muthusamy, Karthik, Pinto e Vairo, Filippo, Klee, Eric W., Lanpher, Brendan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654171/
https://ncbi.nlm.nih.gov/pubmed/33167890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-020-01159-y
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