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Implementation of the therapeutic use of hydroxyurea for sickle cell disease management in resource-constrained settings: a systematic review of adoption, cost and acceptability

OBJECTIVES: Mortality associated with sickle cell disease (SCD) is high in many low- and middle-income countries (LMICs). Hydroxyurea, a medicine to effectively manage SCD, is not widely available in resource-constrained settings. We identified and synthesised the reported implementation outcomes fo...

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Pubblicato in:BMJ Open
Autori principali: Ryan, Nessa, Dike, Lotanna, Ojo, Temitope, Vieira, Dorice, Nnodu, Obiageli, Gyamfi, Joyce, Peprah, Emmanuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654121/
https://ncbi.nlm.nih.gov/pubmed/33168553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-038685
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