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Src Couples Estrogen Receptor to the Anticipatory Unfolded Protein Response and Regulates Cancer Cell Fate Under Stress

Accumulation of unfolded protein, or other stresses, activates the classical reactive unfolded protein response (UPR). In the recently characterized anticipatory UPR, receptor-bound estrogen, progesterone and other mitogenic hormones rapidly elicit phosphorylation of phospholipase C γ (PLCγ), activa...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Res
Main Authors: Yu, Liqun, Wang, Lawrence, Kim, Ji Eun, Mao, Chengjian, Shapiro, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653967/
https://ncbi.nlm.nih.gov/pubmed/32502618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2020.118765
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