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Mitochondrial hyperactivity as a potential therapeutic target in Parkinson’s disease

Mitochondrial dysfunction is thought to contribute to neurodegeneration in Parkinson’s disease (PD), yet the cellular events that lead to mitochondrial disruption remain unclear. Post-mortem studies of PD patient brains and the use of complex I inhibitors to model the disease previously suggested a...

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Bibliographic Details
Published in:Transl Med Aging
Main Authors: Mor, Danielle E., Murphy, Coleen T.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653964/
https://ncbi.nlm.nih.gov/pubmed/33178902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tma.2020.07.007
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