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Drug-target interactions prediction using marginalized denoising model on heterogeneous networks

BACKGROUND: Drugs achieve pharmacological functions by acting on target proteins. Identifying interactions between drugs and target proteins is an essential task in old drug repositioning and new drug discovery. To recommend new drug candidates and reposition existing drugs, computational approaches...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Tang, Chunyan, Zhong, Cheng, Chen, Danyang, Wang, Jianyi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653902/
https://ncbi.nlm.nih.gov/pubmed/32703151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03662-8
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