DeepCryoPicker: fully automated deep neural network for single protein particle picking in cryo-EM

BACKGROUND: Cryo-electron microscopy (Cryo-EM) is widely used in the determination of the three-dimensional (3D) structures of macromolecules. Particle picking from 2D micrographs remains a challenging early step in the Cryo-EM pipeline due to the diversity of particle shapes and the extremely low s...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Al-Azzawi, Adil, Ouadou, Anes, Max, Highsmith, Duan, Ye, Tanner, John J., Cheng, Jianlin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653784/
https://ncbi.nlm.nih.gov/pubmed/33167860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03809-7
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