Articular chondrocyte-derived extracellular vesicles promote cartilage differentiation of human umbilical cord mesenchymal stem cells by activation of autophagy

BACKGROUND: Umbilical cord mesenchymal stem cell (HUCMSC)-based therapies were previously utilised for cartilage regeneration because of the chondrogenic potential of MSCs. However, chondrogenic differentiation of HUCMSCs is limited by the administration of growth factors like TGF-β that may cause c...

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Bibliografiske detaljer
Udgivet i:J Nanobiotechnology
Main Authors: Ma, Ke, Zhu, Bo, Wang, Zetao, Cai, Peian, He, Mingwei, Ye, Danyan, Yan, Guohua, Zheng, Li, Yang, Lujun, Zhao, Jinmin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653755/
https://ncbi.nlm.nih.gov/pubmed/33167997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00708-0
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