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Heregulin induces resistance to lapatinib‐mediated growth inhibition of HER2‐amplified cancer cells

Human epidermal growth factor receptor 2 (HER2) amplification occurs in approximately 20% of gastric and gastroesophageal junction cancers in the United States and European Union. Lapatinib, a dual HER2 and epidermal growth factor receptor tyrosine kinase inhibitor, has demonstrated clinical efficac...

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Detalles Bibliográficos
Publicado en:Cancer Sci
Main Authors: Sato, Yuji, Yashiro, Masakazu, Takakura, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653524/
https://ncbi.nlm.nih.gov/pubmed/24112719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12290
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