The different central nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer

BACKGROUND: Brain metastasis is common in non-small cell lung cancer (NSCLC) and has an even higher incidence in epidermal growth factor receptor (EGFR)-mutant cancers. Although EGFR tyrosine kinase inhibitors (TKIs) are effective against brain metastases, it is unknown which first- or second-genera...

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Veröffentlicht in:Transl Lung Cancer Res
Hauptverfasser: Jung, Hyun Ae, Woo, Sook Young, Lee, Se-Hoon, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Sun, Jong-Mu
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653133/
https://ncbi.nlm.nih.gov/pubmed/33209598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-20-379
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