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Neuroprotective potential of the oxindole alkaloids isomitraphylline and mitraphylline in human neuroblastoma SH-SY5Y cells

The purified oxindole alkaloids, isomitraphylline and mitraphylline from Uncaria perrottetii, revealed their ability to break amyloid aggregates in vitro suggesting their therapeutic potentials in Alzheimer’s disease (AD). Thioflavin-T assay for assessing amyloid-beta (Aβ) aggregation of these alkal...

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Publicat a:3 Biotech
Autors principals: Tan, Mario A., An, Seong Soo A.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652979/
https://ncbi.nlm.nih.gov/pubmed/33194521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-020-02535-4
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