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The application of deep learning for the classification of correct and incorrect SNP genotypes from whole-genome DNA sequencing pipelines

A downside of next-generation sequencing technology is the high technical error rate. We built a tool, which uses array-based genotype information to classify next-generation sequencing–based SNPs into the correct and the incorrect calls. The deep learning algorithms were implemented via Keras. Seve...

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Detalhes bibliográficos
Publicado no:J Appl Genet
Main Authors: Kotlarz, Krzysztof, Mielczarek, Magda, Suchocki, Tomasz, Czech, Bartosz, Guldbrandtsen, Bernt, Szyda, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652806/
https://ncbi.nlm.nih.gov/pubmed/32996082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-020-00586-0
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