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MGMIN: A Normalization Method for Correcting Probe Design Bias in Illumina Infinium HumanMethylation450 BeadChips

The Illumina Infinium HumanMethylation450 Beadchips have been widely utilized in epigenome-wide association studies (EWAS). However, the existing two types of probes (type I and type II), with the distribution of measurements of probes and dynamic range different, may bias downstream analyses. Here,...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Wang, Zhenxing, Liu, Yongzhuang, Wang, Yadong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652792/
https://ncbi.nlm.nih.gov/pubmed/33193611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.538492
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