Generation of a Transplantable Population of Human iPSC-Derived Retinal Ganglion Cells

Optic neuropathies are a major cause of visual impairment due to retinal ganglion cell (RGC) degeneration. Human induced-pluripotent stem cells (iPSCs) represent a powerful tool for studying both human RGC development and RGC-related pathological mechanisms. Because RGC loss can be massive before th...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Rabesandratana, Oriane, Chaffiol, Antoine, Mialot, Antoine, Slembrouck-Brec, Amélie, Joffrois, Corentin, Nanteau, Céline, Rodrigues, Amélie, Gagliardi, Giuliana, Reichman, Sacha, Sahel, José-Alain, Chédotal, Alain, Duebel, Jens, Goureau, Olivier, Orieux, Gael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652757/
https://ncbi.nlm.nih.gov/pubmed/33195235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.585675
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