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RNMFMDA: A Microbe-Disease Association Identification Method Based on Reliable Negative Sample Selection and Logistic Matrix Factorization With Neighborhood Regularization

Microbes with abnormal levels have important impacts on the formation and development of various complex diseases. Identifying possible Microbe-Disease Associations (MDAs) helps to understand the mechanisms of complex diseases. However, experimental methods for MDA identification are costly and time...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Peng, Lihong, Shen, Ling, Liao, Longjie, Liu, Guangyi, Zhou, Liqian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652725/
https://ncbi.nlm.nih.gov/pubmed/33193260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.592430
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