Association Between the Efficacy of Pembrolizumab and Low STK11/LKB1 Expression in High-PD-L1-expressing Non-small-cell Lung Cancer

Background/Aim: STK11/LKB1 mutation has been suggested as a poorly responding candidate biomarker of the anti-programmed cell death-1 (PD-1) antibody; however, the association between STK11/LKB1 expression and the effects of anti-PD-1 antibodies is uncertain. The aim of the study was to correlate th...

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Publicat a:In Vivo
Autors principals: HASEGAWA, TSUKASA, YANAGITANI, NORIKO, NINOMIYA, HIRONORI, SAKAMOTO, HIROAKI, TOZUKA, TAKEHIRO, YOSHIDA, HIROSHI, AMINO, YOSHIAKI, UEMATSU, SHINYA, YOSHIZAWA, TAKAHIRO, ARIYASU, RYO, UCHIBORI, KEN, KITAZONO, SATORU, HORIIKE, ATSUSHI, NISHIO, MAKOTO
Format: Artigo
Idioma:Inglês
Publicat: International Institute of Anticancer Research 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652526/
https://ncbi.nlm.nih.gov/pubmed/32871843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.12131
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