Myeloid transformation by MLL-ENL depends strictly on C/EBP

Chromosomal rearrangements of the mixed-lineage leukemia gene MLL1 are the hallmark of infant acute leukemia. The granulocyte-macrophage progenitor state forms the epigenetic basis for myelomonocytic leukemia stemness and transformation by MLL-type oncoproteins. Previously, it was shown that the est...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Life Sci Alliance
Prif Awduron: Wesolowski, Radoslaw, Kowenz-Leutz, Elisabeth, Zimmermann, Karin, Dörr, Dorothea, Hofstätter, Maria, Slany, Robert K, Mildner, Alexander, Leutz, Achim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Life Science Alliance LLC 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652399/
https://ncbi.nlm.nih.gov/pubmed/33144337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000709
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