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Exploring the Complexity of Protein-Level Dosage Compensation that Fine-Tunes Stoichiometry of Multiprotein Complexes

Proper control of gene expression levels upon various perturbations is a fundamental aspect of cellular robustness. Protein-level dosage compensation is one mechanism buffering perturbations to stoichiometry of multiprotein complexes through accelerated proteolysis of unassembled subunits. Although...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Ishikawa, Koji, Ishihara, Akari, Moriya, Hisao
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652333/
https://ncbi.nlm.nih.gov/pubmed/33112847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009091
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