TAMI-58. A NOVEL ROLE FOR REST IN THE CONTROL OF THE MEDULLOBLASTOMA MICROENVIRONMENT

The REI Silensing Transcription Factor (REST) is a transcriptional repressor and a canonical regulator of neurogenesis. Its expression is elevated in human sonic hedgehog (SHH) subgroup of medulloblastomas (MBs), where functional studies shown its elevated expression to promote proliferation and blo...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Shaik, Shavali, Maegawa, Shinji, Sharma, Ajay, Haltom, Amanda, Dobson, Tara, Yang, Yanwen, Schadler, Keri, Gopalakrishnan, Vidya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651665/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.945
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