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PATH-04. THE BLOOD-BRAIN BARRIER IN DIFFUSE MIDLINE GLIOMA AND ITS IMPLICATIONS FOR DRUG DELIVERY

INTRODUCTION: Chemotherapy has been unsuccessful for pediatric diffuse midline glioma (DMG) most likely due to an intact blood-brain barrier (BBB). However, the BBB has not been characterized in DMG and therefore its implications for drug delivery are unknown. In this study we characterized the BBB...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Haumann, Rianne, El-Khouly, Fatma, Breur, Marjolein, van Zanten, Sophie Veldhuijzen, Kaspers, Gertjan, Hendrikse, Harry, Hulleman, Esther, van Vuurden, Dannis, Bugiani, Marianna
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651628/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.686
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