EPCO-01. LUNG ADENOCARCINOMA BRAIN METASTASIS PREDICTION, PREVENTION, AND NON-INVASIVE DIAGNOSIS USING METHYLATION SIGNATURES WITHIN TISSUE AND CIRCULATING TUMOUR DNA

BACKGROUND: One quarter of lung adenocarcinoma (LUAD) patients develop brain metastases (BM) and experience a poorer median survival of 12 months despite treatment. Clinical variables do not robustly predict who will develop BM and targeted preventative treatments are limited. Tumour DNA methylation...

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Publicat a:Neuro Oncol
Autors principals: Zuccato, Jeffrey, Mamatjan, Yasin, Patil, Vikas, Nassiri, Farshad, Voisin, Mathew, Aldape, Kenneth, Zadeh, Gelareh
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
(Epi)Genetics and Computational Omics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651532/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.280
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