EXTH-04. INTRATHECAL (IT) DELIVERY OF TYPE I POLARIZED DENDRITIC CELL VACCINE (DC1) ERADICATES TUMOR GROWTH IN BREAST CANCER (BC) XENOGRAFT MODEL WITH BRAIN METASTASES (BM) AND LEPTOMENINGEAL DISEASE (LMD)

BACKGROUND: Approx. 5% of BM will also develop LMD. Currently there is no effective treatment for BC-associated BM/LMD. As systemic therapies do not prevent the disease recurrence and eventual death, the better option would be direct-targeted approach. We have shown that there is a loss of the anti-...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Law, Vincent, Kodumudi, Krithika, Snyder, Colin, Czerniecki, Brian, Forsyth, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Preclinical Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651405/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.358
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