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IMMU-03. EFFECT OF COMBINING IRRADIATION AND ANTI-CD47 TREATMENT ON THE PHAGOCYTOSIS OF NORMAL BRAIN CELLS

Immunotherapy using CD47 blockade has shown promise in treating adult and pediatric malignant primary central nervous system tumors. We recently demonstrated that irradiation significantly enhanced anti-CD47-dependent phagocytosis of high-grade glioma cells in vitro. Furthermore, mice engrafted with...

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Publicat a:Neuro Oncol
Autors principals: Hamrick, Forrest, Youssef, Osama, Cheshier, Samuel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651399/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.434
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