TAMI-14. NANOPARTICLE DELIVERY OF PD-L1 CRISPR/CAS9 PLASMID DNA FOR ANTI-GLIOBLASTOMA IMMUNOTHERAPY

Glioblastoma multiforme (GBM) is a devastating cancer that develops from astrocytes in the brain. GBM is fast acting and kills 90% of patients within 5 years. Several immunotherapies have been developed to treat GBM, however, major challenges still persist. For example, checkpoint proteins such as p...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Fierro, Javier, Tran, An, Factoriza, Chris, Chin, Brandon, Dou, Huanyu
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651369/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.903
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