PATH-24. DETECTION OF POINT MUTATIONS AND GENE FUSIONS FROM CIRCULATING CELL-FREE DNA (CFDNA) OF GLIOBLASTOMA (GBM) PATIENTS

BACKGROUND: GBM is characterized by intratumoral heterogeneity. Tumor heterogeneity, clonal diversity and mutation acquisition hamper the ability to tailor personalized therapy for GBM. Tumor sampling has limited ability to accurately capture the molecular landscape of the tumor and to disclose acqu...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Frenkel-Morgenstern, Milana, Palande, Vikrant, Detroja, Rajesh, Gorohovski, Alessandro, Glass, Rainer, Flueh, Charlotte, Kanner, Andrew A, Laviv, Yoseph, Nof, Sagi Har, Levy-Barda, Adva, Benouaich-Amiel, Alexandra, Yust-Katz, Shlomit, Kurtz, Marina, Perez, Shira, Shay, Dorith Raviv, Siegal, Tali
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Molecular Pathology & Classification
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651325/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.705
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