PATH-24. DETECTION OF POINT MUTATIONS AND GENE FUSIONS FROM CIRCULATING CELL-FREE DNA (CFDNA) OF GLIOBLASTOMA (GBM) PATIENTS

BACKGROUND: GBM is characterized by intratumoral heterogeneity. Tumor heterogeneity, clonal diversity and mutation acquisition hamper the ability to tailor personalized therapy for GBM. Tumor sampling has limited ability to accurately capture the molecular landscape of the tumor and to disclose acqu...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Frenkel-Morgenstern, Milana, Palande, Vikrant, Detroja, Rajesh, Gorohovski, Alessandro, Glass, Rainer, Flueh, Charlotte, Kanner, Andrew A, Laviv, Yoseph, Nof, Sagi Har, Levy-Barda, Adva, Benouaich-Amiel, Alexandra, Yust-Katz, Shlomit, Kurtz, Marina, Perez, Shira, Shay, Dorith Raviv, Siegal, Tali
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Molecular Pathology & Classification
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651325/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.705
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