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NCOG-24. WAKE FOREST NCORP RESEARCH BASE FEASIBILITY STUDY OF RAMIPRIL FOR PREVENTING COGNITIVE DECLINE IN GLIOBLASTOMA PATIENTS RECEIVING BRAIN RADIOTHERAPY (WF-1801)

INTRODUCTION: Chronic neuro-inflammation after brain radiotherapy (RT) contributes to radiation-induced cognitive decline (RICD). The renin angiotensin system (RAS) may mediate this inflammatory cascade after RT. Ramipril is an angiotensin-converting enzyme inhibitor used to treat hypertension and h...

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Publicat a:Neuro Oncol
Autors principals: Cramer, Christina, Page, Brandi, Wefel, Jeffrey S, Dressler, Emily, Ip, Edward, Rapp, Steve, Shaw, Edward, Weaver, Kathryn, Lesser, Glenn, Chan, Michael
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651320/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.562
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