EPCO-31. EPIGENOMIC INTRATUMORAL HETEROGENEITY OF GLIOBLASTOMA IN THREE-DIMENSIONAL SPACE

Treatment failure in glioblastoma is often attributed to intratumoral heterogeneity (ITH), which fosters tumor evolution and generation of therapy-resistant clones. While ITH in glioblastoma has been well-characterized at the genomic and transcriptomic levels, the extent of ITH at the epigenomic lev...

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Publicat a:Neuro Oncol
Autors principals: Mathur, Radhika, Iyyanki, Sriranga, Hilz, Stephanie, Hong, Chibo, Phillips, Joanna, Chang, Susan, Yue, Feng, Costello, Joseph
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
(Epi)Genetics and Computational Omics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651235/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.310
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