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INNV-28. TEMOZOLOMIDE IN RENAL DYSFUNCTION

BACKGROUND: Temozolomide (TMZ) is a cytotoxic DNA alkylating agent. It is the only chemotherapy known to improve survival in patients with high grade astrocytomas. The active alkylating species, methylhydrazine, is not recovered in the urine and thus renal function is not expected to affect clearanc...

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發表在:Neuro Oncol
Main Authors: Garzio, Kayla, McElroy, Kelly, Grossman, Stuart, Holdhoff, Matthias, Ozer, Byram, Yankulina, Olga
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651152/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.511
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