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INNV-28. TEMOZOLOMIDE IN RENAL DYSFUNCTION

BACKGROUND: Temozolomide (TMZ) is a cytotoxic DNA alkylating agent. It is the only chemotherapy known to improve survival in patients with high grade astrocytomas. The active alkylating species, methylhydrazine, is not recovered in the urine and thus renal function is not expected to affect clearanc...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Garzio, Kayla, McElroy, Kelly, Grossman, Stuart, Holdhoff, Matthias, Ozer, Byram, Yankulina, Olga
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651152/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.511
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