EPCO-32. AN EPIGENETIC SINGLE-CELL ATLAS OF IDH-MUTANT GLIOMA REVEALS THE ROLE OF ATRX IN SHAPING TUMOR COMPOSITION

Recent single-cell RNA-sequencing studies have identified a hierarchy of cell types that is common to all isocitrate dehydrogenase (IDH) -mutant gliomas. This finding is somewhat paradoxical since the genetic differences between IDH-mutant astrocytomas and IDH-mutant oligodendrogliomas are prognosti...

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Vydáno v:Neuro Oncol
Hlavní autoři: Babikir, Husam, Wang, Lin, Shamardani, Karin, Sudhir, Sweta, Kohanbash, Gary, Aghi, Manish, Philips, Joanna, Diaz, Aaron
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
(Epi)Genetics and Computational Omics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650893/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.311
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