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Pharmacological Modulation of Blood–Brain Barrier Permeability by Kinin Analogs in Normal and Pathologic Conditions

The blood–brain barrier (BBB) is a major obstacle to the development of effective diagnostics and therapeutics for brain cancers and other central nervous system diseases. Peptide agonist analogs of kinin B1 and B2 receptors, acting as BBB permeabilizers, have been utilized to overcome this barrier....

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Publicado en:Pharmaceuticals (Basel)
Main Authors: Sikpa, Dina, Whittingstall, Lisa, Savard, Martin, Lebel, Réjean, Côté, Jérôme, McManus, Stephen, Chemtob, Sylvain, Fortin, David, Lepage, Martin, Gobeil, Fernand
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650794/
https://ncbi.nlm.nih.gov/pubmed/33003415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13100279
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