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Deep Tumor Penetration of Doxorubicin-Loaded Glycol Chitosan Nanoparticles Using High-Intensity Focused Ultrasound

The dense extracellular matrix (ECM) in heterogeneous tumor tissues can prevent the deep tumor penetration of drug-loaded nanoparticles, resulting in a limited therapeutic efficacy in cancer treatment. Herein, we suggest that the deep tumor penetration of doxorubicin (DOX)-loaded glycol chitosan nan...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Choi, Yongwhan, Han, Hyounkoo, Jeon, Sangmin, Yoon, Hong Yeol, Kim, Hyuncheol, Kwon, Ick Chan, Kim, Kwangmeyung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650702/
https://ncbi.nlm.nih.gov/pubmed/33076520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12100974
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