CTNI-39. PHASE 1B CLINICAL TRIAL OF OKN-007 IN RECURRENT MALIGNANT GLIOMA

BACKGROUND: The nitrone compound OKN-007 is a novel anti-cancer agent. In glioblastoma xenografts, OKN-007 reduces cell proliferation and angiogenesis, and increases apoptosis. Here we report on the safety, efficacy, and pharmacokinetics (PK) of OKN-007 in adults with recurrent glioma. METHODS: NCT0...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Battiste, James, Ikeguchi, Alexandra, Woo, Sukyung, Sharan, Satish, Zhao, Yan, Cohoon, Andrew, Sung, Sarah, Wright, Deborah, Teague, April, Jensen, Randy, Kim, Eun Ha, Yang, Won, Towner, Rheal
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Clinical Trials: Non-Immunologic
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650506/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.206
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