DDRE-26. TARGETING THE UNFOLDED PROTEIN RESPONSE POTENTIATES MARIZOMIB ANTITUMOR ACTIVITY IN GLIOBLASTOMA

Glioblastoma (GBM) is the most prevalent and aggressive malignant tumor of the central nervous system in adults. Patients with GBM have a poor prognosis, with a median survival of 15 months with current standard-of-care treatment, consisting of surgery followed by radiotherapy with concomitant and a...

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Опубликовано в: :Neuro Oncol
Главные авторы: Severin, Christophe, Benitez-Hernandez, Jorge, Dumitru, C Dan, Beltran-Raygoza, Nishdallyh, Flandin-Blety, Pierre, Escoubet, Laure, Rolfe, Mark
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Drug Discovery, Drug Resistance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650415/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.271
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