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BIOM-30. DECREASED B CELL AND ALTERED CD4+ T CELL SUBSET RATIO PREDICT FAVORABLE RESPONSE TO RUXOLINITIB IN HIGH-GRADE GLIOMAS

Altered cellular growth and suppression of anti-tumor immune response collectively drive progression and therapeutic resistance of high-grade gliomas (HGGs), suggesting that successful treatments will likely target these key mechanisms. Janus-associated kinase (JAK)-STAT pathway comprises one such t...

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Publicat a:Neuro Oncol
Autors principals: Rauf, Yasmeen, Jia, Xuefei, Lathia, Justin, Peereboom, David, Ahluwalia, Manmeet
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650403/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.029
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