CTIM-25. ONCOLYTIC VIRUS FOR DIPG: THE CLINICAL EXPERIENCE WITH DNX-2401

Despite our increased understanding of Diffuse Intrinsic Pontine Glioma (DIPG) the outcome remains dismal. Recently we showed that the virus Delta-24-RGD (DNX-2401 in the clinic) was effective in preclinical models of DIPG and had the ability to trigger an antitumor immune response. These data allow...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: M Alonso, Marta, Iñigo-Marco, Ignacio, Garcia-Moure, Marc, González-Huarriz, Marisol, Jones, Chris, MACKAY, Alan, Hulleman, Esther, Van der Lugt, Jasper, De Andrea, Carlos, Villalba, Maria, Hernandez, Ruben, Hervás, Sandra, Tamayo, Ibon, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan, Diez-Valle, Ricardo, de Larraya, Jaime Gállego-pérez, Tejada, Sonia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Clinical Trials: Immunologic
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650359/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.159
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