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BIOM-34. CLINICAL, RADIOGRAPHIC, AND PATHOLOGIC PREDICTORS OF RESPONSE TO ANTI-PD-1 AND ANTI-PD-L1 THERAPY IN IDH-WILDTYPE GLIOBLASTOMA PATIENTS

BACKGROUND: Although monoclonal antibodies targeting PD-1 and its ligand PD-L1 have improved overall survival (OS) for many cancers, recent trials of anti-PD-(L)1 in glioblastoma revealed no OS benefit. However, a small subset of patients appears to benefit, warranting evaluation of predictive marke...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Iorgulescu, Bryan, Lim-Fat, Mary Jane, Qin, Lei, Grant, Gareth, Huang, Raymond, Young, Geoffrey, Reardon, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650344/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.033
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