CSIG-20. L3MBTL3 SUPPRESSES MEDULLOBLASTOMA TUMORIGENESIS THROUGH MODULATION OF THE NOTCH/RBPJ SIGNALING PATHWAY

The NOTCH/RBPJ pathway governs cell proliferation in many biological contexts, including SHH and Group#3medulloblastoma (MB) tumorigenesis. Using our proteomic platform, we discovered an interaction between RBPJ, a key co-factor of NOTCH for the modulation of the NOTCH/RBPJ signaling pathway, and L3...

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Vydáno v:Neuro Oncol
Hlavní autoři: Zhang, Honglai, Xu, Tao, Peabody, Claire, Fernández, Ester Calvo, Budhathoki, Rashmi, Huang, Philip Chi-En, Hughes, Elizabeth D, Saunders, Thomas L, Kuick, Rork, Magnuson, Brian, Camelo-Piragua, Sandra, Rual, Jean-François
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Cell Signaling and Signaling Pathways
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650321/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.132
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