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Structural basis for the core-mannan biosynthesis of cell wall fungal-type galactomannan in Aspergillus fumigatus

Fungal cell walls and their biosynthetic enzymes are potential targets for novel antifungal agents. Recently, two mannosyltransferases, namely core-mannan synthases A (CmsA/Ktr4) and B (CmsB/Ktr7), were found to play roles in the core-mannan biosynthesis of fungal-type galactomannan. CmsA/Ktr4 is an...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Hira, Daisuke, Onoue, Takuya, Oka, Takuji
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650258/
https://ncbi.nlm.nih.gov/pubmed/32873705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013742
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