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Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia
Mutations in the skeletal muscle ryanodine receptor gene (RYR1) can cause susceptibility to malignant hyperthermia (MH), a potentially lethal genetic condition triggered by volatile anesthetics. MH is associated with hypermetabolism, which has directed research interest into oxidative phosphorylatio...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7650246/ https://ncbi.nlm.nih.gov/pubmed/32826313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013537 |
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