Combined subthalamic and nucleus basalis of Meynert deep brain stimulation for Parkinson’s disease with dementia (DEMPARK-DBS): protocol of a randomized, sham-controlled trial

INTRODUCTION: Dementia in Parkinson’s disease (PDD) is a common non-motor symptom of advanced disease, associated with pronounced neocortical cholinergic deficits due to neurodegeneration of the nucleus basalis of Meynert (NBM) and its cholinergic terminals. In advanced PD, patients often require ad...

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Detalhes bibliográficos
Publicado no:Neurol Res Pract
Main Authors: Daniels, Christine, Steigerwald, Frank, Capetian, Philipp, Matthies, Cordula, Malzahn, Uwe, Heuschmann, Peter U., Volkmann, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Clinical Trial Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650115/
https://ncbi.nlm.nih.gov/pubmed/33324941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s42466-020-00086-w
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