Protocol of a randomized, double-blind, placebo-controlled, parallel-group, multicentre study of the efficacy and safety of nicotinamide in patients with Friedreich ataxia (NICOFA)

INTRODUCTION: Currently, no treatment that delays with the progression of Friedreich ataxia is available. In the majority of patients Friedreich ataxia is caused by homozygous pathological expansion of GAA repeats in the first intron of the FXN gene. Nicotinamide acts as a histone deacetylase inhibi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Neurol Res Pract
Main Authors: Reetz, Kathrin, Hilgers, Ralf-Dieter, Isfort, Susanne, Dohmen, Marc, Didszun, Claire, Fedosov, Kathrin, Kistermann, Jennifer, Mariotti, Caterina, Durr, Alexandra, Boesch, Sylvia, Klopstock, Thomas, Rodríguez de Rivera Garrido, Francisco Javier, Schöls, Ludger, Klockgether, Thomas, Pandolfo, Massimo, Korinthenberg, Rudolf, Lavin, Philip, Molenberghs, Geert, Libri, Vincenzo, Giunti, Paola, Festenstein, Richard, Schulz, Jörg B.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Clinical Trial Protocol
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650055/
https://ncbi.nlm.nih.gov/pubmed/33324899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s42466-019-0038-9
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker